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Chip Based Common-path Swept-source Optical Coherence Tomography Device

机译:基于芯片的共路扫频光学相干层析成像设备

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摘要

Optical coherence tomography (OCT) is an optical imaging technique which provides three-dimensional images with micrometer-resolution. OCT has been extensively used for disease diagnostics, treatment planning, and surgical guidance. Currently, most of the OCT systems are based on discrete free-space optical components and optical fibers. These discrete components keep these instruments costly and bulky. The development in integrated optical circuit technology provides the opportunity to develop miniaturized, stable and maintenance-free OCT systems. The goal of this study is developing an OCT chip with external light source and detector. The developed chip is intended to be used in a hand-held OCT probe for skin applications. In this study, a literature survey summarized the achievements and limitations of current chip-based OCT systems. Our common-path design uses the end facet of the waveguide as the reference plane, thus eliminating the need for a space-consuming and dispersive on-chip loop reference arm, thereby reducing the chip size and obviating the need for dispersion compensation. Our on-chip micro-ball lens eliminates the need of external optical elements for coupling the light between the chip and the sample, thereby further reducing the size and the complexity of the system. The signal to noise ratio (SNR) of our system was measured to be 71 dB with 2.6 mW of power on a mirror sample at a distance of 0.3 mm from the waveguide end facet. At this moment, the SNR of our chip system is slightly lower (11 dB lower) than a fiber-based system under the same experimental condition. The suggestions for improving the SNR of our chip system were discussed. Multiple ghost images caused by additional reference planes (originating from the lens surface) could be largely suppressed using a deconvolution scheme. Finally, we presented the design and fabrication results of a common-path parallel SS-OCT (PSS-OCT) chip followed by suggestions for characterization measurements and for possible improvements in the parallel chip design. We believe that by integrating a micro-ball lens onto the chip and using a common-path configuration we have moved a significant step forward in the development of on-chip SS-OCT systems.
机译:光学相干断层扫描(OCT)是一种光学成像技术,可提供具有微米分辨率的三维图像。 OCT已被广泛用于疾病诊断,治疗计划和手术指导。当前,大多数OCT系统都基于离散的自由空间光学组件和光纤。这些分立的组件使这些仪器既昂贵又笨重。集成光电路技术的发展为开发小型,稳定且免维护的OCT系统提供了机会。这项研究的目标是开发具有外部光源和检测器的OCT芯片。该开发的芯片旨在用于皮肤应用的手持式OCT探头。在这项研究中,一项文献调查总结了当前基于芯片的OCT系统的成就和局限性。我们的公共路径设计使用波导的端面作为参考平面,从而消除了对占用空间且分散的片上环路参考臂的需求,从而减小了芯片尺寸,并消除了色散补偿的需要。我们的片上微球透镜无需外部光学元件即可将光耦合到芯片和样品之间,从而进一步降低了系统的尺寸和复杂性。在距波导器端面0.3 mm的反射镜样本上,以2.6 mW的功率测量时,我们系统的信噪比(SNR)为71 dB。目前,在相同的实验条件下,我们的芯片系统的SNR稍低于基于光纤的系统(低11 dB)。讨论了改善我们芯片系统信噪比的建议。使用反卷积方案可以大大抑制由附加参考平面(源自镜头表面)引起的多个重影图像。最后,我们介绍了共路径并行SS-OCT(PSS-OCT)芯片的设计和制造结果,并提出了表征测量和并行芯片设计可能的改进建议。我们相信,通过将微球镜集成到芯片上并使用公共路径配置,我们已经在片上SS-OCT系统的开发方面迈出了重要的一步。

著录项

  • 作者

    Chang, Lantian;

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  • 年度 2016
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  • 原文格式 PDF
  • 正文语种 en
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